Say it eight times real fast! Spidey's #2 greatest villain!

Otto Octavious. Otto Octavious. Say that three times real fast and you'll get a brief understanding of the difficulty, not just in pronunciation, but in many amazing battles between the web-slinger and the intellectual greatness of the man who became Dr. Octopus.

Although most bad guys tend to fit a mold of greed and insidiousness, Otto was originally a decent, but highly advanced researcher, deeply submerged in his work until an unfortunate explosion bonded his mechanical harness to his spine. Shortly thereafter, the four writhing limbs would fall completely under his command, giving him many advantages in combat, maneuvering, and pure physical leverage. More...

If you're interested in seeing some other foes of Spidey, check out The Top 10 Villains of Spider-Man, a weekly countdown list that goes all the way to #1, provided by TSL. And remember, if you like superheroes, check out the List!